All Posts tagged Ostera

Osteoporosis & Vitamin C Update

Journal PLoS One provides evidence that vitamin C, when ingested orally, can prevent bone loss (osteoporosis) and stimulate the formation of new bone (in mice).

The medical world has known for some time that low amounts of vitamin C can cause scurvy and brittle bones, and that higher vitamin C intake is associated with higher bone mass in humans.

Large doses of vitamin C, when ingested orally by mice, actively stimulate bone formation to protect the skeleton. It does this by inducing osteoblasts, or premature bone cells, to differentiate into mature, mineralizing specialty cells.

This data provides compelling evidence for a therapeutic potential for vitamin C. Mice with ovariectomies were divided into two groups, one of which was given large doses of vitamin C over eight weeks. The team then measured the bone mineral density in the lumbar spine, femur and tibia bones. The lead researcher Zaidi revealed that mice who received an ovariectomy without vitamin C had a much lower bone mineral density than those that received a “sham” operation. Mice with no ovaries but given large doses of vitamin C had roughly the same bone mineral density as the controls, suggesting vitamin C prevented bone density losses in this group.

Could simple inexpensive dietary supplements versus expensive drugs help prevent osteoporosis? I think so! I also like to use Ostera from Metagenics.

PLoS One.

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Vitamin D3 & Bone Health

The Interactive Healer
DrJeffreyTucker.com 

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July 30, 2010 

 

 
In This Issue
Dr. Tucker’s New E-Book Released!
Vitamin D
Improve Posture
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Dear Dr. Jeff,
Dr. Jeffrey Tucker

This week’s newsletter offers you tips for when to take vitamin D, as well as supplements for osteoporosis and important exercises for maintaining good posture. 
Keep checking www.DrJeffreyTucker.com so I can keep you updated on important and valuable health information. 
If you have any questions, suggestions or comments, please feel free to email Dr. Tucker at:  DrJTucker@aol.com

 

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Osteoporosis & Ostera 

 

Ostera (a natural supplement from Metagenics) versus the new crop of osteoporosis drugs such as denosumab. Let’s see: 
Denosumab is given by injection
Denosumab may cost more than $10,000 per year
Denosumab works by affecting the immune system, so the long-term effects on immune function and cancer risk are unknown and will need to be tracked by the FDA.

Or would you rather try something less-expensive and drug- free?

 

Ostera! A supplement that promotes healthy bone remodeling in postmenopausal women. Researchers at Metaproteomics, a nutrigenomic research and development company employing more than 40 scientists and physicians at its research centers in the US and Europe, developed Ostera. Drawing on the anti-inflammatory properties of hops, as well as other unique nutritional agents like berberine and acacia, Ostera is a potent promoter of bone-remodeling.

 

Osteoporosis is actually an INFLAMMATORY DISEASE. Inflammation accelerates bone loss. But all of us tend toward inflammation as we age, and this body-wide process does not exempt the bones. The realization that inflammation is at the core of osteoporosis has prompted investigation into new drug therapies that specifically target bone inflammation. One such drug is denosumab, now in clinical trials. Denosumab is a breakthrough bio-engineered monoclonal antibody. This new Amgen drug has shown significant benefits in clinical trials, and promises to be a block-buster once it’s approved within a couple of years. But it’s certain to be VERY expensive, and it requires injections to work. I predict these new drugs will arrive at an opportune time: just when the medical establishment and the public will be in full retreat from the current crop of medications, as their limitations and side effects become increasingly evident. 

 

Ostera, in combination with a Mediterranean-style, low-glycemic-load diet and aerobic exercise, has been clinically shown in postmenopausal women to beneficially influence key biomarkers of bone remodeling more than diet and exercise alone.

 
When Ostera was field-tested on 77 postmenopausal women with low estrogen. It produced dramatic improvements (greater than 40%) in markers of bone turnover. Those patients adding Ostera to there arsenal of natural therapies for osteoporosis will further enhance there results, sometimes even after a few short months of treatment. 
Ostera is perfectly safe with other natural supplements and prescribed medications.
Dr. Tucker’s osteoporosis recommendation: 
Cal Apatite Forte Capsules  Daily supplements of vitamin D and calcium.
Ostera A safe natural alternative for bone support.
Sources:
“Studies: New Osteoporosis Drug Cuts Fracture Risk” Linda A. Johnson, Associated Press, 8/11/09, ap.org

 

More on Vitamin D…

 

Vitamin D intake is important for muscle function, bone health, fighting cancer, improving heart health, and preventing type 2 diabetes. That’s why I think more is better… 
The International Osteoporosis Foundation supports raising the recommended daily intake of vitamin D to:
1) Daily intake of 800 to 1,000 IU
2) Daily intake of 2,000 for those who have osteoporosis, get limited sun exposure, or are obese.

This higher dosage is absolutely a step in the right direction, but it’s just starting to approach the daily D intake I recommend – between 2,000 and 3,000 IU daily, and 5,000 IU daily for those over the age of 40. 

Wake Forest University researchers examined data from a study that measured blood levels of D in more than 2,780 elderly subjects. Three blood samples were taken from each subject over the course of four years. Results showed that higher blood levels of D were linked to better physical function, while about 90 percent of subjects with the lowest D levels had poorer physical function. 

TIP: You may be able to significantly boost your vitamin D levels by following one simple habit: Take D supplements with your largest meal of the day. Researchers at the Cleveland Clinic Foundation Bone Clinic recruited 17 subjects who had remained vitamin D deficient even after being treated for their deficiency.

For 2-3 months, each subject began taking their D supplements with the largest meal of the day. Dosage levels varied from 1,000 to 50,000 IU daily.

Results: Overall, absorption of the vitamin was improved and blood levels of D increased by more than 50 percent when D was taken at a meal. 

Take Home Point: Take vitamin D supplements at lunch or dinner time.

 

I recommend Iso D3. Either the 2000 IU or 5000 IU depending on age and exposure to sunshime. Iso D3 is the preferred form of vitamin D3 with Isoflavones.

 

 

These exercises prevent the natural progression of kyphosis (rounded back)

Rounded shoulders & slumped posture increases in healthy men & women with age, with the most rapid increase occurring between 50 and 60 years. The progression of rounded shoulders was prevented in those performed these extension exercises three times a week for one year. 
Like everything else I teach you, compliance is important.
Exercises which strengthen the extensor muscles of the spine can delay the progression of hyperkyphosis (rounded back).

 

Source: Ball et al. Department of Physical Therapy Education, School of Allied Health, University of Kansas Medical Center, Kansas, KS, USA.

 

 

 

 

Feel free to forward our newsletter to your friends, family and coworkers.  And please feel free to contact me with your questions, comments and suggestions. 
Please stay committed to your health, fitness and nutrition efforts.
 
Warm regards,
 
 

 

Dr. Jeffrey Tucker
 

 

Dr. Tucker is certified in using the Functional Movement Screen (FMS) & just returned from Danville, VA with the developers of the FMS. When you start a fitness plan, it’s vital to be prepared. Commitment isn’t measureable, but physical readiness is. The FMS evaluates whether your body is ready to take on a fitness plan, puts you on the road to genuine wellness, and tracks your progress along the way. Dr. Tucker will be happy to perform the FMS on you.
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Osteoporosis & Ostera

Osteoporosis is characterized by loss of bone mass and is associated with an increased risk of fracture after falls, particularly in the hip and mid-back. Osteoporotic women are often physically frail as well, leading to disability. Weight-bearing and resistive exercises have been shown to reduce the loss of bone (as measured by bone mineral density). Come in to the office and I can teach you the most specific exercises to perform that will help you prevent further osteoporosis.

A comprehensive supplement for osteoporosis is Ostera by Metagenics. Order @ www.DrJeffreyTucker.meta-ehealth.com

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Fosamax, Boniva, Actonel, and other osteoporosis drugs

The more we find out about this drug, the worse it gets.  If you are on these meds I hope you’ll do your research and consider natural alternatives like Ostera from Metagenics. Using a bisphosphonate drug–especially when taken for several years increases your risk of esophageal cancer. 

Have you ever wondered about those specific instructions that tell bisphosphonate users to drink a full glass of water and not lie down for 30 minutes after taking the drug?  If the drug isn’t swallowed properly, it can irritate the esophagus. If that happens too often, it can cause esophagitis–inflammation of the esophagus. 

A few years ago, Danish researchers reviewed more than 11,000 medical records and found that patients with esophagitis were significantly more likely to develop esophageal cancer.

Recognizing the importance of this potential link, a team of UK researchers examined medical records for more than 78,000 patients. As reported this past September in the British Medical Journal, the UK team found that extended bisphosphonate use (about five years) nearly DOUBLED the risk of esophageal cancer.

This is pretty horrifying when you consider that more than 20 million people have used Fosamax since it was introduced in the 90s. And that’s just one brand of this very popular class of drugs.

I recommend Ostera and Cal-Apatite. These can be ordered @ www.DrJeffreyTucker.meta-ehealth.com

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I’m still upset over this Osteoporosis issue

In the early 80s, few people had even heard of osteoporosis. And it wasn’t until the next decade – 1993 – when the World Health Organization (WHO) created clear definitions of it. This gave firm criteria for doctors to diagnose brittle bones as a disease.

WHO created this guideline: a woman has osteoporosis when her bone mineral density (BMD) is 2.5 deviations below the standard BMD of average healthy young women. The measurement is made by an x-ray exam. Seems pretty straightforward. Women with a T score of -1.0 and -2.5 have osteoporosis.

Except the WHO study was financed by three drug companies. These three companies were the Rorer Foundation, Sandoz, and SmithKline Beecham. The study they funded led to not only defining criteria for diagnosing osteoporosis… But also to establishing it firmly as a marketable disease.

The drug companies stood to benefit greatly if definitions of osteoporosis included large numbers of postmenopausal women. Especially if BMI testing was adopted into routine medical care.

There’s one important point to make here. Women’s bones do become more brittle with age. And hip and thigh fractures are a major cause for concern for women after they hit menopause.

The following year – in 1994 – the WHO study group recommended screenings and interventions. They determined that the “appropriate time” for these tests was menopause. To make sure no one missed it, their recommendation was published in Osteoporosis International. Suddenly, BMD became part of routine care for millions of postmenopausal women. The drug companies were assured that millions would be seeking billions of dollars’ worth of their drugs.

By 1995 Fosamax appeared on the market. The first of the brand new osteoporosis drugs. It was swiftly approved by the FDA. Osteoporosis screenings, treatment, and drugs became part of the American lifestyle. Almost overnight.

But there has never been any proof to show that any of these steps actually help women whatsoever.

What is safe and effective for bone nutrition and osteoporosis prevention? Weight bearing exercise and the supplement Cal Apatite with Magnesium by Metagenics. If you already have osteopenia (bone loss) or osteoporosis then you need  Ostera by Metagenics. Order from www.DrJeffreyTucker.meta-ehealth.com

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Osteoporosis drugs are getting to be a joke!

The FDA has warned osteoporosis patients that the very drugs they take to strengthen their bones… may be making them even weaker. For the past several years I’ve talked to my patients about reports that suggest these drugs may increase risk of thigh-bone fracture. Especially in women taking these drugs for five years or more.

Finally the FDA is telling major drug makers to put a warning on their labels. So here’s the “joke” – The FDA is issuing its warning… and stresses that patients shouldn’t quit their drugs! Not unless they start to feel new thigh pain. And not even then. Not until their doctor tells them to quit the drug. But the real issue isn’t that these drugs may be dangerous… It’s that they may not actually do any good at all.

The research that promoted these drugs in the first place was funded by the drug companies that stood to gain the most. The results that prompted the FDA to initially approve the drugs don’t stand up to much scrutiny.

OK, let me get this straight – take one of the drugs listed below thinking you are doing something for osteoporosis, yet these drugs may actually increase the risk of bone fractures. 

  • Actonel
  • Actonel with Calcium
  • Atelvia
  • Boniva
  • Fosamax
  • Fosamax Plus D
  • Reclast and Boniva

Here’s  the FDA statement:

“While it is not clear whether [these drugs] are the cause, a rare but serious type of thigh bone fracture, has been predominantly reported in patients taking [them].”

The FDA has told the manufacturers to put a warning label on their drugs. But it’s told the public to keep taking them… unless their doctor orders them not to.

What is safe for bone nutrition?  I recommend the supplement Cal Apatite with Magnesium by Metagenics. If you already have osteopenia (bone loss) or osteoporosis then you need  Ostera by Metagenics. Order from www.DrJeffreyTucker.meta-ehealth.com

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Bone nutrition (osteoporosis)

I get asked alot about osteoporosis prevention. Clients love to show me there bone density test results. Most people seem to think taking calium by itself is enough to prevent osteoporosis.   Heres what you need to know for bone support – strong bones require more than calcium. Calcium without magnesium doesn’t occur in a natural human diet, so calcium shouldn’t be introduced to the body by itself. For most people to have complete bone nutrition, I recommend calcium, magesium, phosphorus, and vitamin D3.  Some people may need manganese, boron, silica, strontium, digestive enzymes, and often additional betaine hydrochloride, and ALWAYS vitamin D (and high doses of that last one if a lot of calcium is swallowed). 

Calcium alone has been found in several experiments to be improperly laid down in the body, even affecting arterial walls causing the arteries to get smaller (yikes!). 

DON’T take  antacids and think you are getting your calcium. The form of calcium in antacids is an inferior form and actually lowers the acid level (pH) in the stomach, which is necessary for digestion of many nutrients and proteins. 

In my opinion the best supplement for bone nutrition is Cal Apatite with Magnesium by Metagenics. If you already have osteopenia (bone loss) or osteoporosis then you need  Ostera by Metagenics.

www.DrJeffreyTucker.meta-ehealth.com to order

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Omega-3 Fatty Acids Linked to Healthier, Stronger Bones

How Do I Get Stronger Bones?

Increased intakes of omega-3 fatty acids, DHA (docosahexaenoic acid) in particular, may increase bone mineral content and produce healthier, stronger bones, according to a new study involving rats.

Omega-3 fatty acids, most notably EPA (eicosapentaenoic acid) and DHA, have been linked to a wide range of health benefits, including reduced risk of cardiovascular disease, good development of a baby during pregnancy, joint health and improved behavior and mood.

According to findings of the new study with rats, DHA “appears to be a vital constituent of marrow” and enhances bone mineral content (BMC). The findings did not extend to EPA, however.

Scientists from Purdue University, Indiana University School of Medicine, Korea Maritime University and the U.S. National Institutes of Health (NIH), reported their findings in the British Journal of Nutrition.

For stronger bone development I recommend Ostera (Metagenics), Cal Apatite Plus (Metagenics), Vitamin D3 (2-5 grams daily), and EPA-DHA 720 (Metagenics).  Order at www.DrJeffreyTucker.meta-ehealth.com

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Osteoporosis Supplements – Ostera

Metagenics has a product called Ostera, a fully absorbable supplement, for treatment of postmenopausal women who have a high risk for osteoporotic fractures, including those with a history of fracture or multiple risk factors for fracture, or those who have failed or are intolerant to other osteoporosis therapy.

Ostera supports bone health. I highly recommend this natural product over injections or medications with uncertain side effects.

Proper nutrition and exercise reduces the incidence of vertebral, nonvertebral, and hip fractures in postmenopausal women with osteoporosis.

Common side effects of prescribed drugs for Osteoporosis include back pain, pain in the extremities, musculoskeletal pain, high cholesterol levels, and urinary bladder infections. ostera does not have these side effects.

Ostera is manufactured by Metagenics. Please click on the link to Metagenics.

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Long-Term Bisphosphonate Use Linked to Abnormal Bone Formation

An unusual type of bone fracture has been reported in women who have taken bisphosphonates for osteopenia and osteoporosis for more than 4 years, according to 2 studies reported at the American Association of Orthopaedic Surgeons 2010 Annual Meeting.

Joseph Lane, MD, chief of the Metabolic Bone Service at the Hospital for Special Surgery and professor of orthopedic surgery at Weill Cornell Medical College in New York City said concern is mounting that long-term use of these drugs might adversely affect bone quality.

Osteoporosis, a loss of bone mineral density that can occur as we age is a real concern to avoid because 1 in 5 patients who have a hip fracture die within 1 year.

Bisphosphonates have been shown to prevent the rapid loss of bone that occurs during the first years of menopause and to reduce the incidence of fracture in postmenopausal women.

However, there have been reports of “peculiar” fractures — that is, low-energy femur fractures that are seen in patients who have been on long-term bisphosphonate treatment. The first report was published in 2005 in a “semi-obscure” journal, Dr. Lane told Medscape Orthopaedics.

In a second unrelated study, Melvin P. Rosenwasser, MD, Robert E. Carroll Professor of Hand Surgery at Columbia University in New York City, and colleagues evaluated the bone structure of 112 postmenopausal women with primary osteoporosis, 62 of whom had been taking bisphosphonates for at least 4 years, and 50 control subjects who were taking only calcium and vitamin D supplements.

They found that bisphosphonate use improved structural integrity early in the course of treatment, but that these gains were diminished as treatment extended beyond 4 years.

“It seems as if there is a plateau of benefit at 4 or 5 years and, after that, the benefit is negated. In the early treatment period, patients using bisphosphonates experienced improvements in all parameters, including decreased buckling ratio and increased cross-sectional area,” he said in an interview with Medscape Orthopaedics. “But after 4 years of use, these trends reversed.”

Women (and men), If you have been on these drugs for 4 years, consider taking a break and use a natural supplement called Ostera from Metagenics instead.

American Association of Orthopaedic Surgeons (AAOS) 2010 Annual Meeting: Abstract 241, presented March 10, 2010; Abstract 339, presented March 11, 2010.

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