Italian researchers examined the magnesium status of people with mild-to-moderate Alzheimer’s disease (AD). They found those with low-ionized magnesium levels had the most impaired cognitive function compared to a control group.
The magnesium “ion test” in the study showed low magnesium levels in AD, whereas serum total magnesium levels didn’t show a deficiency. “This serves to confirm that magnesium deficiency overexcites the brain’s neurons and results in less coherence and reduced cognitive function,” said Carolyn Dean, MD, ND, magnesium expert and medical director of the Nutritional Magnesium Association.
“The study also validates the fact that serum magnesium levels are a poor way to diagnose magnesium deficiency and that magnesium ion testing is a far more valid way of testing for magnesium deficiency,” she added. “Magnesium in the blood does not correlate with the amount of magnesium in other parts of your body.”
Magnesium deficiency/depletion may be more common than we think. Check your supplements! It is associated with short- and long-term memory.
Magnesium Research 24(3):115-121, 2011