I am definitely not convinced that saturated-fat consumption leads to heart disease. In fact, I see the exact opposite!
Authors of the MR-FIT trial were determined to prove the case. They enrolled 350,000 men, all of whom were considered at high risk of heart disease. In one set of participants, cholesterol consumption was reduced by 42%, saturated fat by 28%, and total calories by 21%.
What happened? Nothing. The authors referred to the results as “disappointing,” stating that “The overall results do not show a beneficial effect on Coronary Heart Disease or total mortality from this multifactor intervention.”
The Women’s Health Initiative was a huge government study, costing almost three quarters of a billion dollars. Among 20,000 women in the study who adhered to a diet low saturated fat diet for eight years, there was no reduction in the rates of heart-disease or stroke.
Then there was the Cochrane Collaboration, in 2000. This group rigorously selected 27 low-fat and cholesterol-lowering trials to review (more than 200 trials were rejected). Their conclusion was that diets low in saturated fat have “no significant effect” on heart attack mortality. Lead researcher Lee Hooper, PhD, said “I was disappointed that we didn’t find something more definitive.”
More recently, the American Journal of Clinical Nutrition published a review of 21 studies. The studies ranged from 5 to 23 years in length and encompassed 347,747 subjects. In the authors’ own words: “Intake of saturated fat was not associated with an increased risk of CHD, stroke, or CVD.”