European Journal of Clinical Nutrition Published online ahead of print.
A daily dose of vitamin B-6 at the current upper tolerable levels may reduce amounts of inflammatory compounds in people suffering from rheumatoid arthritis, a new study says.
Levels of the pro-inflammatory compounds interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) significantly decreased following 12 weeks of supplementation with 100 mg of vitamin B-6, according to findings published in the European Journal of Clinical Nutrition.
However, scientists from Chung Shan Medical University in Taiwan said that no changes were observed for pyridoxal-5-phosphate (PLP), the active form of vitamin B-6, in relation to levels of C-reactive protein (CRP), another marker of inflammation.
After 12 weeks of supplementation with B6, significant decreases in levels of IL-6 and TNF-alpha were observed.
“A large dose of vitamin B-6 supplementation (100 mg per day) suppressed pro-inflammatory cytokines (that is, IL-6 and TNF-alpha) in patients with rheumatoid arthritis,” the researchers concluded.
Vitamin B-6, a water-soluble vitamin that exists as pyridoxine, pyridoxal and pyridoxamine is found in beans, meat, fish and some fruits and vegetables, like spinach and avocado. I recommended UltraInflamX medical shakes from Metagenics as a great source of B6 and other i,portant nutrients for RA and other inflammatory conditions. www.DrJeffreyTucker.meta-ehealth.com to purchase UltraInflamX.