Supplements of chromium picolinate may boost memory function in the elderly, says a new placebo-controlled, double-blind study.
Scientists from the University of Cincinnati College of Medicine report that daily supplements of the compound improved learning, recall and recognition memory tasks.
Researchers stated: “Insulin resistance is implicated in the pathophysiological changes associated with Alzheimer’s disease and pharmaceutical treatments that overcome insulin resistance improve memory function in subjects with mild cognitive impairment (MCI) and early Alzheimer’s disease.
Chromium supplementation improves glucose disposal in patients with insulin resistance and diabetes.” Chromium is an essential trace mineral that occurs naturally in small amounts in some foods, including brewer’s yeast, lean meat, cheese, pork kidney and whole grain breads and cereals. It is poorly absorbed by the human body but is known to play an important role in the metabolism of carbohydrates, fats and proteins.”
Twenty-six older adults were recruited to participate in the study and they were randomly assigned to 1,000 micrograms of chromium picolinate per day (Chromax®, Nutrition 21) or placebo capsules for 12 weeks.
Researchers concluded: “Memory and depression were assessed prior to treatment initiation and during the final week of treatment. We also performed functional magnetic resonance imaging (fMRI) scans on a subset of subjects. Although learning rate and retention were not enhanced by chromium picolinate (CrPic) supplementation, we observed reduced semantic interference on learning, recall and recognition memory tasks. In addition fMRI indicated comparatively increased activation for the CrPic subjects in right thalamic, right temporal, right posterior parietal and biofrontal regions. These findings suggest that supplementation with CrPic can enhance cognitive inhibitory control and cerebral function in older adults at risk for neurodegeneration.”
Nutritional Neuroscience 13(3):116-122, 2010
Comments: I recommend 2 shakes per day of the UltraGlycemX 360 powder or MetaGlycemX (2 tabs per day) or Chromium Picolinate (3 tabs per day) to achieve the proper dose. These are sold by Metagenics.